Nipissing West OPP report two people were taken to hospital with serious but non-life threatening injuries after a collision on Highway 17 on Tuesday.
The highway was closed at Jocko Point for about three hours.
Police say a commercial vehicle and two passenger vehicles were involved.
The investigation is ongoing.
Anyone who may have witnessed the collision or has dashcam footage from the area at the time of the crash is asked to contact the OPP.
